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1

Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice

Zhou, Xin, von der Mark, Klaus, Henry, Stephen, Norton, William, Adams, Henry, de Crombrugghe, Benoit, Warman, Matthew L.

Journal:

Year:

2014

Language:

english

File:

PDF, 52.89 MB

english, 2014

2

The Novel Zinc Finger-Containing Transcription Factor Osterix Is Required for Osteoblast Differentiation and Bone Formation

Kazuhisa Nakashima, Xin Zhou, Gary Kunkel, Zhaoping Zhang, Jian Min Deng, Richard R. Behringer, Benoit de Crombrugghe

Journal:

Year:

2002

Language:

english

File:

PDF, 1.09 MB

english, 2002

3

Dual control for transcription of the galactose operon by cyclic AMP and its receptor protein at two interspersed promoters

Musso, Richard E., Di Lauro, Roberto, Adhya, Sankar, de Crombrugghe, Benoit

Journal:

Year:

1977

Language:

english

File:

PDF, 6.07 MB

english, 1977

4

The gene for the homeodomain-containing protein Cart-1 is expressed in cells that have a chondrogenic potential during embryonic development

Zhao, Guang-Quan, Eberspaecher, Heidi, Seldin, Michael F., de Crombrugghe, Benoit

Journal:

Mechanisms of Development

Year:

1994

Language:

english

File:

PDF, 21.24 MB

english, 1994

5

Effect of Rho on Transcription of Bacterial Operons

DE CROMBRUGGHE, BENOIT, ADHYA, SANKAR, GOTTESMAN, MAX, PASTAN, IRA

Journal:

Nature New Biology

Year:

1973

File:

PDF, 575 KB

1973

6

Parallel expression of Sox9 and Col2a1 in cells undergoing chondrogenesis

Qi Zhao, Heidi Eberspaecher, Véronique Lefebvre, Benoit de Crombrugghe

Journal:

Developmental Dynamics

Year:

1997

Language:

english

File:

PDF, 621 KB

english, 1997

7

Transcriptional regulation of fibronectin gene by phorbol myristate acetate in hepatoma cells: A negative role for NF-κB

Byung-Heon Lee, Min-Seung Kim, Jung-Hwa Rhew, Rang-Woon Park, Benoit de Crombrugghe, In-San Kim

Journal:

Journal of Cellular Biochemistry

Year:

2000

Language:

english

File:

PDF, 258 KB

english, 2000

8

Activation of a fibroblast-specific enhancer of the Proα2(I) collagen gene in tight-skin mice

Christopher P. Denton, Bing Zheng, Xu Shiwen, Zhaoping Zhang, George Bou-Gharios, Heidi Eberspaecher, Carol M. Black, Benoit De Crombrugghe

Journal:

Arthritis & Rheumatism

Year:

2001

Language:

english

File:

PDF, 1.14 MB

english, 2001

9

Developmental expression of a type II collagen/β-galactosidase fusion gene in transgenic mice

Marjo Metsäranta, Silvio Garofalo, Chad Smith, Karen Niederreither, Benoit De Crombrugghe, Eero Vuorio

Journal:

Developmental Dynamics

Year:

1995

Language:

english

File:

PDF, 5.10 MB

english, 1995

10

Postnatal induction of transforming growth factor β signaling in fibroblasts of mice recapitulates clinical, histologic, and biochemical features of scleroderma

Sonali Sonnylal, Christopher P. Denton, Bing Zheng, Douglas R. Keene, Ruming He, Henry P. Adams, Carolyn S. VanPelt, Yong J. Geng, Jenny M. Deng, Richard R. Behringer, Benoit de Crombrugghe

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 1.47 MB

english, 2007

11

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis

Sonali Sonnylal, Xu Shi-Wen, Patricia Leoni, Katherine Naff, Caroline S. Van Pelt, Hiroyuki Nakamura, Andrew Leask, David Abraham, George Bou-Gharios, Benoit de Crombrugghe

Journal:

Arthritis & Rheumatism

Year:

2010

Language:

english

File:

PDF, 476 KB

english, 2010

12

Generation of aggrecan-CreERT2 knockin mice for inducible Cre activity in adult cartilage

Stephen P. Henry, Chuan-Wei Jang, Jian Min Deng, Zhaoping Zhang, Richard R. Behringer, Benoit de Crombrugghe

Journal:

Year:

2009

Language:

english

File:

PDF, 597 KB

english, 2009

13

Sox9-expressing precursors are the cellular origin of the cruciate ligament of the knee joint and the limb tendons

Tsunemitsu Soeda, Jian Min Deng, Benoit de Crombrugghe, Richard R. Behringer, Takashi Nakamura, Haruhiko Akiyama

Journal:

Year:

2010

Language:

english

File:

PDF, 1.03 MB

english, 2010

14

Transforming growth factor-β isoforms differently stimulate proα2 (I) collagen gene expression during wound healing process in transgenic mice

Takuro Kinbara, Fumiaki Shirasaki, Shigeru Kawara, Yutaka Inagaki, Benoit de Crombrugghe, Kazuhiko Takehara

Journal:

Journal of Cellular Physiology

Year:

2002

Language:

english

File:

PDF, 230 KB

english, 2002

15

Downregulation of a rheumatoid arthritis-related antigen (RA-A47) by ra-a47 antisense oligonucleotides induces inflammatory factors in chondrocytes

Takako Hattori, Harumi Kawaki, Satoshi Kubota, Yasutaka Yutani, Benoit de Crombrugghe, Klaus von der Mark, Masaharu Takigawa

Journal:

Journal of Cellular Physiology

Year:

2003

Language:

english

File:

PDF, 263 KB

english, 2003

16

Downregulation of rheumatoid arthritis-related antigen RA-A47 (HSP47/colligin-2) in chondrocytic cell lines induces apoptosis and cell-surface expression of RA-A47 in association with CD9

Takako Hattori, Klaus von der Mark, Harumi Kawaki, Yasutaka Yutani, Satoshi Kubota, Tohru Nakanishi, Heidi Eberspaecher, Benoit de Crombrugghe, Masaharu Takigawa

Journal:

Journal of Cellular Physiology

Year:

2005

Language:

english

File:

PDF, 646 KB

english, 2005

17

BAC constructs in transgenic reporter mouse lines control efficient and specific LacZ expression in hypertrophic chondrocytes under the complete Col10a1 promoter

Sonja Gebhard, Takako Hattori, Eva Bauer, Michael R. Bösl, Britta Schlund, Ernst Pöschl, Nadia Adam, Benoit de Crombrugghe, Klaus von der Mark

Journal:

Histochemistry and Cell Biology

Year:

2007

Language:

english

File:

PDF, 652 KB

english, 2007

18

Cyclic AMP regulates Catabolite and Transient Repression in E. coli

PERLMAN, ROBERT L., DE CROMBRUGGHE, BENOIT, PASTAN, IRA

Journal:

Year:

1969

File:

PDF, 339 KB

1969

19

Unusual location and function of the operator in the Escherichia coli galactose operon

DiLauro, Roberto, Taniguchi, Taketoshi, Musso, Richard, de Crombrugghe, Benoit

Journal:

Year:

1979

File:

PDF, 850 KB

1979

20

Regulation of a collagen gene promoter by the product of viral mos oncogene

Schmidt, Azriel, Setoyama, Chiaki, de Crombrugghe, Benoit

Journal:

Year:

1985

File:

PDF, 537 KB

1985

21

10.1038/8792

Behringer, Richard R., de Crombrugghe, Benoit, Bi, Weimin, Deng, Jian Min, Zhang, Zhaoping

Journal:

Nature Genetics

Year:

1999

Language:

english

File:

PDF, 1.90 MB

english, 1999

22

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase

Yasuda, Hideyo, Sinha, Krishna M, Coombes, Madelene M, Dent, Sharon Y R, de Crombrugghe, Benoit

Journal:

The EMBO Journal

Year:

2009

Language:

english

File:

PDF, 2.00 MB

english, 2009

23

Prenatal folic acid treatment suppresses acrania and meroanencephaly in mice mutant for the Cart1 homeobox gene

Zhao, Qi, Behringer, Richard R., de Crombrugghe, Benoit

Journal:

Nature Genetics

Year:

1996

File:

PDF, 1.26 MB

1996

24

Normal long bone growth and development in type X collagen-null mice

Rosati, Rita, Horan, Gerald S. B., Pinero, Gerald J., Garofalo, Silvio, Keene, Douglas R., Horton, William A., Vuorio, Eero, de Crombrugghe, Benoit, Behringer, Richard R.

Journal:

Nature Genetics

Year:

1994

File:

PDF, 1.26 MB

1994

25

NFAT and Osterix cooperatively regulate bone formation

Koga, Takako, Matsui, Yuichi, Asagiri, Masataka, Kodama, Tatsuhiko, de Crombrugghe, Benoit, Nakashima, Kazuhisa, Takayanagi, Hiroshi

Journal:

Nature Medicine

Year:

2005

Language:

english

File:

PDF, 701 KB

english, 2005

26

Positive Regulation of Adult Bone Formation by Osteoblast-Specific Transcription Factor Osterix

Wook-Young Baek, Min-A Lee, Ji Won Jung, Shin-Yoon Kim, Haruhiko Akiyama, Benoit de Crombrugghe, Jung-Eun Kim

Journal:

Journal of Bone and Mineral Research

Year:

2009

Language:

english

File:

PDF, 3.64 MB

english, 2009

27

Genetic evidence for the vital function of osterix in cementogenesis

Zhengguo Cao, Hua Zhang, Xin Zhou, Xianglong Han, Yinshi Ren, Tian Gao, Yin Xiao, Benoit de Crombrugghe, Martha J Somerman, Jian Q Feng

Journal:

Journal of Bone and Mineral Research

Year:

2012

Language:

english

File:

PDF, 864 KB

english, 2012

28

Osteoblast-Specific Expression of the α2(I) Collagen Promoter in Transgenic Mice: Correlation with the Distribution of TGF-β1

Rena N. D'Souza, Karen Niederreither, Benoit de Crombrugghe

Journal:

Journal of Bone and Mineral Research

Year:

1993

Language:

english

File:

PDF, 5.22 MB

english, 1993

29

Specific hybridization probes for mouse α2(IX) and α1(X) collagen mRNAs

Kati Elima, Marjo Metsäranta, Johanna Kallio, Merja Perälä, Iiro Eerola, Silvio Garofalo, Benoit De Crombrugghe, Eero Vuorio

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

1992

Language:

english

File:

PDF, 412 KB

english, 1992

30

Transcriptional mechanisms in osteoblast differentiation and bone formation

Kazuhisa Nakashima, Benoit de Crombrugghe

Journal:

Trends in Genetics

Year:

2003

Language:

english

File:

PDF, 1.25 MB

english, 2003

31

Regulatory mechanisms in the pathways of cartilage and bone formation

Benoit de Crombrugghe, Véronique Lefebvre, Kazuhisa Nakashima

Journal:

Current Opinion in Cell Biology

Year:

2001

Language:

english

File:

PDF, 403 KB

english, 2001

32

Role of the CCAAT-binding protein CBF/NF-Y in transcription

Sankar N Maity, Benoit de Crombrugghe

Journal:

Trends in Biochemical Sciences

Year:

1998

Language:

english

File:

PDF, 672 KB

english, 1998

33

Activation of Proα2(I) Collagen Promoter during Hepatic Fibrogenesis in Transgenic Mice

Yutaka Inagaki, Sharada Truter, George Bou-Gharios, Lee Ann Garrett, Benoit de Crombrugghe, Tomoyuki Nemoto, Patricia Greenwel

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 218 KB

english, 1998

34

rDlx, a Novel Distal-less-like Homeoprotein Is Expressed in Developing Cartilages and Discrete Neuronal Tissues

Guang-Quan Zhao, Shourong Zhao, Xin Zhou, Heidi Eberspaecher, Michael Solursh, Benoit de Crombrugghe

Journal:

Developmental Biology

Year:

1994

File:

PDF, 2.45 MB

1994

35

Chromosomal Assignment and Tissue Expression of CBF-C/NFY-C, the Third Subunit of the Mammalian CCAAT-Binding Factor

Satrajit Sinha, Sankar N. Maity, Michael F. Seldin, Benoit de Crombrugghe

Journal:

Year:

1996

Language:

english

File:

PDF, 451 KB

english, 1996

36

V-Fos stimulates expression of the α1(III) collagen gene in NIH 3T3 cells

Chiaki Setoyama, Atsushi Hatamochi, Beverly Peterkofsky, Willie Prather, Benoit de Crombrugghe

Journal:

Biochemical and Biophysical Research Communications

Year:

1986

Language:

english

File:

PDF, 809 KB

english, 1986

37

Conservation of binding sites for regulatory factors in the coordinately expressed α1(I) and α2(I) collagen promoters

Gerard Karsenty, Benoit de Crombrugghe

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 990 KB

english, 1991

38

Molecular cloning and characterization of a novel rat activin receptor

Randy Legerski, Xin Zhou, Julie Dresback, Heidi Eberspaecher, Sandra McKinney, Patricia Segarini, Benoit de Crombrugghe

Journal:

Biochemical and Biophysical Research Communications

Year:

1992

Language:

english

File:

PDF, 1023 KB

english, 1992

39

Purification of a novel factor which binds to the mouse α2 (I) collagen promoter

Atsushi Hatamochi, Benoit de Crombrugghe, Thomas Krieg

Journal:

Year:

1993

Language:

english

File:

PDF, 1.02 MB

english, 1993

40

Tenascin-W inhibits proliferation and differentiation of preosteoblasts during endochondral bone formation

Hiroaki Kimura, Haruhiko Akiyama, Takashi Nakamura, Benoit de Crombrugghe

Journal:

Biochemical and Biophysical Research Communications

Year:

2007

Language:

english

File:

PDF, 751 KB

english, 2007

41

Sclerostin is a direct target of osteoblast-specific transcription factor osterix

Fan Yang, Wanjin Tang, Sarah So, Benoit de Crombrugghe, Chi Zhang

Journal:

Biochemical and Biophysical Research Communications

Year:

2010

Language:

english

File:

PDF, 367 KB

english, 2010

42

Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification

Jung-Hoon Oh, Seung-Yoon Park, Benoit de Crombrugghe, Jung-Eun Kim

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 1.48 MB

english, 2012

43

Characterization of Dkk1 gene regulation by the osteoblast-specific transcription factor Osx

Chi Zhang, Hui Dai, Benoit de Crombrugghe

Journal:

Biochemical and Biophysical Research Communications

Year:

2012

Language:

english

File:

PDF, 379 KB

english, 2012

44

Dkk1 is a possible direct target of Osx

Chi Zhang, Benoit de Crombrugghe

Journal:

Year:

2008

Language:

english

File:

PDF, 53 KB

english, 2008

45

Postnatally induced inactivation of Osterix in osteoblasts results in the reduction of bone formation and maintenance

Wook-Young Baek, Benoit de Crombrugghe, Jung-Eun Kim

Journal:

Year:

2010

Language:

english

File:

PDF, 1.41 MB

english, 2010

46

Osteoblasts Clock in for Their Day Job

Benoit de Crombrugghe

Journal:

Year:

2005

Language:

english

File:

PDF, 42 KB

english, 2005

47

Joint Formation Requires Muscle Formation and Contraction

Hideyo Yasuda, Benoit de Crombrugghe

Journal:

Developmental Cell

Year:

2009

Language:

english

File:

PDF, 94 KB

english, 2009

48

Expression of master regulatory genes controlling skeletal development in benign cartilage and bone forming tumors

Jane Y. Dancer, Stephen P. Henry, Jolanta Bondaruk, Sangkyou Lee, Alberto G. Ayala, Benoit de Crombrugghe, Bogdan Czerniak

Journal:

Human Pathology

Year:

2010

Language:

english

File:

PDF, 1.66 MB

english, 2010

49

The transcription factor Sox9 is degraded by the ubiquitin–proteasome system and stabilized by a mutation in a ubiquitin-target site

Haruhiko Akiyama, Tetsu Kamitani, Xiaohong Yang, Roshini Kandyil, Laura C. Bridgewater, Marc Fellous, Yuko Mori-Akiyama, Benoit de Crombrugghe

Journal:

Year:

2005

Language:

english

File:

PDF, 432 KB

english, 2005

50

A highly conserved enhancer in mammalian type X collagen genes drives high levels of tissue-specific expression in hypertrophic cartilage in vitro and in vivo

Sonja Gebhard, Ernst Pöschl, Silvia Riemer, Eva Bauer, Takako Hattori, Heidi Eberspaecher, Zhaoping Zhang, Veronique Lefebvre, Benoit de Crombrugghe, Klaus von der Mark

Journal:

Year:

2004

Language:

english

File:

PDF, 694 KB

english, 2004

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